Product Name A-769662
Product Code CM901508
Description A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an a? heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the 1 subunit. A-769662 activates AMPK through the subunit carbohydrate-binding module and the ? subunit but not the AMP-binding sites. A-769662 stimulated partially purified rat liver AMPK with an EC50 of 0.8 M and inhibited fatty acid synthesis in primary rat hepatocytes with an IC50 of 3.2 M.
CAS Number 844499-71-4
Formula C20H12N2O3S
MW 360.4 Da
Product Type Inhibitor
Grade =99%
Storage Condition refer to Technology Column

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