| Identifiers |
| Product Name |
A 83-01
|
| Product Code |
CM726671 |
| Description |
A selective inhibitor of TGF-ß type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-ß-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs). |
| Application |
1 mg. Purity:>98% by HPLC. CAS1 909910-43-6. A selective inhibitor of TGF-ß type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 a |
| CAS Number |
909910-43-6 |
| Formula |
C25H19N5S |
| MW |
421.52 |
| Storage Condition |
-20°C |
