Identifiers
Product Name A 83-01
Product Code CM726671
Description A selective inhibitor of TGF- type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF--induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs).
Application 1 mg. Purity:>98% by HPLC. CAS1 909910-43-6. A selective inhibitor of TGF- type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 a
CAS Number 909910-43-6
Formula C25H19N5S
MW 421.52
Storage Condition -20C

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